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Search Results to Fenghuang Zhan

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One or more keywords matched the following items that are connected to Zhan, Fenghuang

Item TypeName
Academic Article The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma.
Academic Article The distinct gene expression profiles of chronic lymphocytic leukemia and multiple myeloma suggest different anti-apoptotic mechanisms but predict only some differences in phenotype.
Academic Article RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.
Academic Article Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma.
Academic Article Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.
Academic Article CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
Academic Article Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis.
Academic Article Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma.
Academic Article Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival.
Academic Article Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma.
Academic Article Antibody-based inhibition of DKK1 suppresses tumor-induced bone resorption and multiple myeloma growth in vivo.
Academic Article Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance.
Academic Article ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma.
Academic Article NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.
Academic Article High-risk myeloma: a gene expression based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed disease treated with single-agent bortezomib or high-dose dexamethasone.
Academic Article Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2.
Academic Article High expression of BCL3 in human myeloma cells is associated with increased proliferation and inferior prognosis.
Academic Article NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses.
Academic Article The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells.
Academic Article Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells.
Academic Article Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma.
Academic Article Activated protein C resistance as measured by residual factor V after Russell's viper venom and activated protein C treatment analyzed as a continuous variable in multiple myeloma and normal controls.
Academic Article RARalpha2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma.
Academic Article Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells.
Academic Article An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma.
Concept Bacterial Proteins
Concept Calcium-Binding Proteins
Concept Microtubule-Associated Proteins
Concept Carrier Proteins
Concept DNA-Binding Proteins
Concept Protein Kinases
Concept Membrane Proteins
Concept Protein C
Concept Protein-Tyrosine Kinases
Concept Microfilament Proteins
Concept Proteins
Concept CDC2 Protein Kinase
Concept Protein Conformation
Concept Proto-Oncogene Proteins
Concept Activated Protein C Resistance
Concept Repressor Proteins
Concept Oncogene Proteins
Concept Recombinant Proteins
Concept Ribosomal Proteins
Concept Cation Transport Proteins
Concept rab GTP-Binding Proteins
Concept Proto-Oncogene Proteins p21(ras)
Concept Early Growth Response Protein 1
Concept Inhibitor of Apoptosis Proteins
Concept Protein Binding
Concept Proto-Oncogene Proteins c-jun
Concept Tumor Suppressor Protein p53
Concept Proto-Oncogene Proteins c-myc
Concept Ubiquitin-Protein Ligases
Concept Multidrug Resistance-Associated Proteins
Concept Adaptor Proteins, Signal Transducing
Concept bcl-X Protein
Concept Wnt Proteins
Concept Protein Stability
Concept JNK Mitogen-Activated Protein Kinases
Concept Heat-Shock Proteins
Concept Extracellular Matrix Proteins
Concept ras Proteins
Concept Tumor Suppressor Proteins
Concept Protein Biosynthesis
Concept Cell Cycle Proteins
Concept Protein Phosphatase 2
Concept Protein Tyrosine Phosphatases
Concept Intercellular Signaling Peptides and Proteins
Concept Receptors, G-Protein-Coupled
Concept Proto-Oncogene Proteins c-kit
Concept Protein Kinase Inhibitors
Concept Zebrafish Proteins
Concept Nuclear Factor 90 Proteins
Concept Neoplasm Proteins
Concept Proto-Oncogene Proteins c-bcl-2
Concept S-Phase Kinase-Associated Proteins
Concept Hedgehog Proteins
Concept Protein Isoforms
Concept Proto-Oncogene Proteins c-akt
Concept p38 Mitogen-Activated Protein Kinases
Academic Article Expression of PAX5 in CD20-positive multiple myeloma assessed by immunohistochemistry and oligonucleotide microarray.
Academic Article Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts.
Academic Article Myeloma cell-derived Runx2 promotes myeloma progression in bone.
Academic Article Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.
Grant Gene expression profiling vs MRD assessment in Myeloma
Academic Article Inhibition of Nek2 by small molecules affects proteasome activity.
Academic Article Bruton tyrosine kinase is a therapeutic target in stem-like cells from multiple myeloma.
Academic Article Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation.
Academic Article Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus.
Academic Article NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase.
Academic Article Multiple Myeloma Tumor Cells are Selectively Killed by Pharmacologically-dosed Ascorbic Acid.
Academic Article RARa2 expression confers myeloma stem cell features.
Academic Article NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma.
Academic Article Nek2 is a novel regulator of B cell development and immunological response.
Academic Article Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma.
Academic Article Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome.
Academic Article NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.
Academic Article A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Academic Article Neoplastic plasma cell aberrant antigen expression patterns and their association with genetic abnormalities.
Academic Article Ferroportin downregulation promotes cell proliferation by modulating the Nrf2-miR-17-5p axis in multiple myeloma.
Academic Article TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.
Academic Article Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model.
Academic Article Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma.
Academic Article Down-regulation of 11?-hydroxysteroid dehydrogenase type 2 by bortezomib sensitizes Jurkat leukemia T cells against glucocorticoid-induced apoptosis.
Academic Article Overexpression of RPS27a contributes to enhanced chemoresistance of CML cells to imatinib by the transactivated STAT3.
Academic Article NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma.
Academic Article Polycomb-like Protein 3 Induces Proliferation and Drug Resistance in Multiple Myeloma and Is Regulated by miRNA-15a.
Grant Retinoid Based Treatment Approaches to Target the Myeloma Stem Cell
Grant NEK2 Over-expression Causes Drug Resistance in Myeloma
Academic Article RFWD2 induces cellular proliferation and selective proteasome inhibitor resistance by mediating P27 ubiquitination in multiple myeloma.
Academic Article Monitoring treatment response and disease progression in myeloma with circulating cell-free DNA.
Academic Article GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice.
Academic Article The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Academic Article RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth.
Academic Article HNRNPA2B1 promotes multiple myeloma progression by increasing AKT3 expression via m6A-dependent stabilization of ILF3 mRNA.
Academic Article PHF19 inhibition as a therapeutic target in multiple myeloma.
Grant Targeting NEK2 Enables Immune Checkpoint Blockade in High-Risk/Relapsed Myeloma
Academic Article TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies.
Academic Article Role of NEK2A in human cancer and its therapeutic potentials.
Academic Article WDR26 and MTF2 are therapeutic targets in multiple myeloma.
Academic Article FOXM1 regulates glycolysis and energy production in multiple myeloma.
Academic Article AKT supports the metabolic fitness of multiple myeloma cells by?restricting FOXO activity.
Academic Article Aberrant activation of TRIP13-EZH2 signaling axis promotes stemness and therapy resistance in multiple myeloma.
Academic Article Decreased bone resorption in Ezh2 myeloid cell conditional knockout mouse model.
Academic Article Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma.

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  • GTP Binding Proteins